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Broad-spectrum injectable nematodicide.
COMPOSITION:
Each mL of LEVAMISOLE 15% Erma® contains:
Levamisole hydrochloride 150 mg
Aqueous vehicle q.s. to 1 mL
PROPERTIES:
LEVAMISOLE 15% Erma® is safe for use during pregnancy, parturition, and in newborn animals.
Acts as a cholinergic nematodicide, stimulating nicotinic receptors in susceptible worms, causing excitatory–spastic paralysis and subsequent expulsion or death.
Interferes with carbohydrate metabolism by inhibiting fumarate reductase and succinate oxidation.
Also exhibits immunostimulatory effects in immunocompromised animals, enhancing cellular immunity, leukocyte migration, T-lymphocyte activity, and phagocytic capacity of monocytes.
INDICATIONS:
Treatment of parasitic infestations caused by:
Cattle, sheep, and goats: Gastrointestinal nematodes (Trichostrongylus spp., Haemonchus placei, Ostertagia spp., Cooperia spp., Strongyloides spp., Oesophagostomum spp., Nematodirus spp., Bunostomum spp., Chabertia ovina, Neoascaris vitulorum) and lungworms (Dictyocaulus viviparus, Dictyocaulus filaria).
Swine: Gastrointestinal nematodes (Ascaris suum, Hyostrongylus spp., Oesophagostomum spp.) and lungworms (Metastrongylus apri).
DOSAGE AND ROUTE OF ADMINISTRATION:
Cattle: Subcutaneous (neck or behind the shoulder) or deep intramuscular (thigh or rump).
Swine: Subcutaneous (behind the ear) or deep intramuscular (ham).
Sheep and goats: Subcutaneous (behind the shoulder or groin).
DOSAGE:
Administer 5 mg/kg body weight, equivalent to 1 mL per 30 kg body weight.
Do not exceed 11 mL per animal in animals weighing over 330 kg.
In heavily infested herds, repeat treatment after 15 days, as directed by the veterinarian.
WITHDRAWAL PERIOD:
Meat: 72 hours after the end of treatment.
Milk: Milk produced during treatment and for 24 hours after must not be used for human consumption.
CONTRAINDICATIONS AND PRECAUTIONS:
Contraindicated in horses. Do not use in equines.
Do not administer intravenously (risk of intoxication and death).
Toxicity signs resemble organophosphate poisoning (cholinergic signs). Atropine may be used as an antidote.
Toxicity risk increases when used with pyrantel, diethylcarbamazine, or organophosphates.
PRESENTATION:
Vials containing 100 mL and 500 mL of injectable solution.
USE IN: Cattle, swine, sheep, and goats.
Broad-spectrum injectable nematodicide.
COMPOSITION:
Each mL of LEVAMISOLE 15% Erma® contains:
Levamisole hydrochloride 150 mg
Aqueous vehicle q.s. to 1 mL
PROPERTIES:
LEVAMISOLE 15% Erma® is safe for use during pregnancy, parturition, and in newborn animals.
Acts as a cholinergic nematodicide, stimulating nicotinic receptors in susceptible worms, causing excitatory–spastic paralysis and subsequent expulsion or death.
Interferes with carbohydrate metabolism by inhibiting fumarate reductase and succinate oxidation.
Also exhibits immunostimulatory effects in immunocompromised animals, enhancing cellular immunity, leukocyte migration, T-lymphocyte activity, and phagocytic capacity of monocytes.
INDICATIONS:
Treatment of parasitic infestations caused by:
Cattle, sheep, and goats: Gastrointestinal nematodes (Trichostrongylus spp., Haemonchus placei, Ostertagia spp., Cooperia spp., Strongyloides spp., Oesophagostomum spp., Nematodirus spp., Bunostomum spp., Chabertia ovina, Neoascaris vitulorum) and lungworms (Dictyocaulus viviparus, Dictyocaulus filaria).
Swine: Gastrointestinal nematodes (Ascaris suum, Hyostrongylus spp., Oesophagostomum spp.) and lungworms (Metastrongylus apri).
DOSAGE AND ROUTE OF ADMINISTRATION:
Cattle: Subcutaneous (neck or behind the shoulder) or deep intramuscular (thigh or rump).
Swine: Subcutaneous (behind the ear) or deep intramuscular (ham).
Sheep and goats: Subcutaneous (behind the shoulder or groin).
DOSAGE:
Administer 5 mg/kg body weight, equivalent to 1 mL per 30 kg body weight.
Do not exceed 11 mL per animal in animals weighing over 330 kg.
In heavily infested herds, repeat treatment after 15 days, as directed by the veterinarian.
WITHDRAWAL PERIOD:
Meat: 72 hours after the end of treatment.
Milk: Milk produced during treatment and for 24 hours after must not be used for human consumption.
CONTRAINDICATIONS AND PRECAUTIONS:
Contraindicated in horses. Do not use in equines.
Do not administer intravenously (risk of intoxication and death).
Toxicity signs resemble organophosphate poisoning (cholinergic signs). Atropine may be used as an antidote.
Toxicity risk increases when used with pyrantel, diethylcarbamazine, or organophosphates.
PRESENTATION:
Vials containing 100 mL and 500 mL of injectable solution.
USE IN: Cattle, swine, sheep, and goats.
